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COVID-19 infection stages are visualized at Inés Colmegna et al., “MSM Insights: Is there a role for cell therapy in SARS-CoV-2 infection?” https://mrm.research.mcgill.ca, based on Hasan K. Siddiqi et al., “COVID-19 illness in native and immunosuppressed states: A clinical−therapeutic staging proposal,” The Journal of Heart and Lung Transplantation, Volume 39, Issue 5, March 2020, 405-407, […]
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Inflammation predisposes to the development of cancer and promotes all stages of tumorigenesis. Cancer cells, as well as surrounding stromal and inflammatory cells, engage in well-orchestrated reciprocal interactions to form an inflammatory tumor microenvironment (TME). Cells within the TME are highly plastic, continuously changing their phenotypic and functional characteristics. Here, we review the origins of
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There are more than 1,300 scientific articles published in peer reviewed scientific journals disclosing adverse effects to COVID-19 vaccination, just to name a few: We estimated an extra two, one and six myocarditis events per 1 million people vaccinated with ChAdOx1, BNT162b2 and mRNA-1273, respectively, in the 28 days following a first dose and
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Clinical signs and symptoms of long COVID can be grouped in the following clusters: Respiratory: shortness of breath, congestion, persistent cough, pulmonary embolism, etc. Neurological/psychiatric: brain fog, malaise, tiredness, headaches, migraines, depression, inability to focus/concentrate, altered cognition, insomnia, vertigo, panic attacks, tinnitus, anosmia, phantom smells, parosmia, etc. Musculoskeletal: myalgias, fatigue, weakness, joint pains, inability to
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Cell death plays an important role in the regulation of inflammation and may be the result of inflammation. The maintenance of tissue homeostasis necessitates both the recognition and removal of invading microbial pathogens as well as the clearance of dying cells. In the past few decades, emerging knowledge on cell death and inflammation has enriched
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Magnesium is a mineral that is important for a variety of bodily functions, including maintaining strong bones, regulating heart rhythm, and supporting the immune system. Vitamin K2 and Magnesium should be supplemented together with Vitamin D3, in order to prevent long-term health-risk and improve immunoregulatory effects based on a causal loop diagram. Magnesium activates protein kinases, stimulates T-cell receptors and production by generating ATP, controls cell membrane inflammation, has vasodilatory and antithrombotic effects, and supresses the cytokine storm. It can be used against migraine headache, metabolic syndrome, diabetes, hyperlipidemia, asthma, premenstrual syndrome, preeclampsia, various cardiac arrhythmias, prevention of renal calculi and cataract formation, and as an adjunct or treatment for depression.
A type of vitamin found in animal-based foods such as meat, cheese, and eggs, as well as fermented foods like natto. It is important for blood clotting and bone health. Vitamin K2 and Magnesium should be supplemented together with Vitamin D3, in order to prevent long-term health-risk and improve immunoregulatory effects based on a causal loop diagram. Vitamin K2 is anticancer, antineoplastic, and together with vitamin D3 is beneficial for bone and cardiovascular health.
A type of vitamin that the body can produce when exposed to sunlight, and is also found in certain foods such as fatty fish and mushrooms. It helps with calcium absorption and maintaining strong bones. It is anti-viral (against e.g. SARS-CoV-2 virus), anti-inflammatory, plays a major role regulating the immune system. Vitamin D3 deficiency may confer increased risk of influenza, respiratory tract infection and HIV infection. Vitamin D3 improves circulation and may prove to be beneficial in the treatment of hypertension and other cardiovascular diseases, including heart failure, myocardial infarction, vasculopathy, stroke and diabetes.
An essential nutrient found in various foods such as carrots, sweet potatoes, and milk. It is important for maintaining healthy vision, skin, and immune function. It is anti-viral (against e.g. SARS-CoV-2 virus), and enhances the innate immune response against pathogens by acting on the major cellular subsets and inducing the release of pro-inflammatory cytokines and antimicrobial peptides, minimize the damage caused by the activation of the immune system against pathogens, reducing the oxidative damage, influencing the antigen presentation, enhancing the differentiation and proliferation of regulatory T cells, driving the differentiation of lymphocyte subsets, and modulating the production of pro-inflammatory cytokines.
A mineral that is important for the functioning of the immune system, taste perception, and wound healing. It can be found in foods such as oysters, beef, and beans. It is anti-viral (against e.g. SARS-CoV-2 virus), and can be used against cardiovascular diseases, affects the heart by modulating cardiomyocyte oxidative stress and maintaining myocardial structure, among other mechanisms.